Volume 5, Issue 18 (4-2015)                   NCMBJ 2015, 5(18): 9-14 | Back to browse issues page

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Ghorbani M. A Review of Type 2 Diabetes and Obesity. NCMBJ. 2015; 5 (18) :9-14
URL: http://ncmbjpiau.ir/article-1-618-en.html
Department of research and Development, Research and ProductionComplex of Pasteur Institute of Iran, Kilometre 25 Tehran-Karaj Highway, Karaj, Iran , mghorbani@irimc.org
Abstract:   (7074 Views)

Here in this paper, we describe the relationship between type 2 diabetes and obesity including different types of obesity and its genetic predisposition. Several physiological conditions that are capable of changing the level of expression of numerous genes involved in metabolic pathways, energy production, and regulating body weight, are created due to the expansion of our modern society and abundance of caloric foods. It appears that a variety of genes could participate in adaptation of human body to its revolutionary limitations. 

Therefore, due to the importance of obesity in relation to metabolic disorders by increasing the visceral adipose tissue, induction of higher level of free fatty acids in the blood and insulin resistance, we conclude that there is a close relationship between the obesity and type 2 diabetes and further genetic analysis in juveniles and at early ages could give a better insight of the occurrence of obesity and its treatment.
Full-Text [PDF 437 kb]   (5559 Downloads)    
Type of Study: Research Article | Subject: Pharmacology
Received: 2015/05/30 | Accepted: 2015/05/30 | Published: 2015/05/30

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