Volume 9, Issue 34 (4-2019)                   NCMBJ 2019, 9(34): 47-56 | Back to browse issues page

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Department of Biology, Faculty of Life Sciences, Islamic Azad University, Parand Parand, Parand, Iran , Vahid55vet@yahoo.com
Abstract:   (3291 Views)
Aim and Background:
In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.
 
Material and methods:
The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic exercise - diabetic and  immobile with green tea extract , diabetic with synergism of exercise and green tea extract. After inducing of diabetes using sterptozotocin mice were killed and in days 3-7-14-21 macroscopic and histopathologic analysis were performed.
 
Results:
The results indicated that in synergistic group of  green tea extract and treadmill exercise , wound area decreased and fibroblast  increased after 7 days significantly compared with other groups (p<0.001).PMN cells decreased after 3 days significantly compared with other groups (p<0.001).
 
Conclusion:
The results suggest that green tea extract and treadmill exercise have synergistic effect on wound healing in diabetic mice.
 
 
 
 
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Type of Study: Research Article | Subject: Cellular and molecular
Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16

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