Volume 12, Issue 46 (3-2022)
NCMBJ 2022, 12(46): 55-64 |
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Department of Microbiology, Faculty of Basic Sciences, Institute of Higher Education, Andisheh Sazan, Mazandaran, Mazandaran
Abstract: (1697 Views)
Aim and Background: Today, microorganisms have become resistant to drugs by causing gene mutations. The aim of this study was to determine the antibiotic resistance of bacteria isolated from urine culture in the laboratory of Savadkuh city.
Material and methods:A cross-sectional descriptive study was performed on bacteria isolated from urinary tract infections in Savadkuh laboratory. Bacteria in the sample were identified by microscopic method, morphological examination and biochemical tests.
Results: Out of 693 samples, the result of urine culture test was 462 positive. Staphylococcus 45.4%, E.Coli (34.6%), Streptococcus (12.9%) and Klebsiella (7.1%) were the most common isolated bacteria, respectively. In the study performed on the pattern of antibiotic resistance, the most cases of resistance were related to the antibiotics ampicillin, cefazolin, trimethoprim, sulfamethoxazole and ciprofloxacin, respectively. On the other hand, the highest susceptibility of bacteria is related to the antibiotics nitrofurantoin, cephalexin, cefotaxime, gentamicin and ceftriaxone, respectively.
Conclusion: According to the results of the study, the most common microorganisms that cause urinary tract infections have been identified and the most appropriate antibiotics have been introduced for treatment, which is very effective in reducing the resistance of bacteria to antibiotics. Treatment costs are also reduced with the use of appropriate antibiotics in the early stages of infection.
Material and methods:A cross-sectional descriptive study was performed on bacteria isolated from urinary tract infections in Savadkuh laboratory. Bacteria in the sample were identified by microscopic method, morphological examination and biochemical tests.
Results: Out of 693 samples, the result of urine culture test was 462 positive. Staphylococcus 45.4%, E.Coli (34.6%), Streptococcus (12.9%) and Klebsiella (7.1%) were the most common isolated bacteria, respectively. In the study performed on the pattern of antibiotic resistance, the most cases of resistance were related to the antibiotics ampicillin, cefazolin, trimethoprim, sulfamethoxazole and ciprofloxacin, respectively. On the other hand, the highest susceptibility of bacteria is related to the antibiotics nitrofurantoin, cephalexin, cefotaxime, gentamicin and ceftriaxone, respectively.
Conclusion: According to the results of the study, the most common microorganisms that cause urinary tract infections have been identified and the most appropriate antibiotics have been introduced for treatment, which is very effective in reducing the resistance of bacteria to antibiotics. Treatment costs are also reduced with the use of appropriate antibiotics in the early stages of infection.
Type of Study: Research Article |
Subject:
Microbiology
Received: 2021/03/27 | Accepted: 2021/11/24 | Published: 2022/04/11
Received: 2021/03/27 | Accepted: 2021/11/24 | Published: 2022/04/11
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