Aim and Background: Microbial infections are important challenges to health, and health care officials have major difficulties dealing with them especially regarding their antibiotic resistance. The main aim

of this study was to evaluate anti-bacterial effects of Cinnamomun Verum and Ferula Gummosa essential oil on some pathogen bacteria.

Materials and Methods: Cinnamomun Verum and Ferula Gummosa essential oil were extracted from its plan. For the evaluation of antibacterial effects of the essential oil, disc diffusion method through the measurement of the inhibitory zone. Minimum Inhibitory concentration (MIC) was detected.

Results: According to the results of disc diffusion test in Agar, Cinnamomun Verum and Ferula Gummosa essential oil, with a 47 mm and 33 mm inhibition zone, manifested the greatest antibacterial activity against Staphylococcus Saprophyticus. It had the greatest positive co-action with gentamicin (10 μg) on Escherichia Coli.

Conclusion: The results of this study indicate that Cinnamomun Verum and Ferula Gummosa essential oil alone or in combination with antimicrobial agents may be useful in the treatment of bacterial infections.