TY - JOUR T1 - A Review of Type 2 Diabetes and Obesity TT - مروری بر ارتباط بین دیابت نوع 2 و چاقی JF - NCMBJ JO - NCMBJ VL - 5 IS - 18 UR - http://ncmbjpiau.ir/article-1-618-en.html Y1 - 2015 SP - 9 EP - 14 KW - Type 2 Diabetes KW - Obesity KW - Metabolism N2 - Here in this paper, we describe the relationship between type 2 diabetes and obesity including different types of obesity and its genetic predisposition. Several physiological conditions that are capable of changing the level of expression of numerous genes involved in metabolic pathways, energy production, and regulating body weight, are created due to the expansion of our modern society and abundance of caloric foods. It appears that a variety of genes could participate in adaptation of human body to its revolutionary limitations. Therefore, due to the importance of obesity in relation to metabolic disorders by increasing the visceral adipose tissue, induction of higher level of free fatty acids in the blood and insulin resistance, we conclude that there is a close relationship between the obesity and type 2 diabetes and further genetic analysis in juveniles and at early ages could give a better insight of the occurrence of obesity and its treatment. M3 ER -