New Cellularand Molecular Biotechnology Journal

fa تاثیر عوامل محیطی در ایجاد سرطان مغز The effect of Environmental Factors in the incidence of Brain Cancer ژنتیک Genetics مقاله پژوهشی Research Article <div style="text-align: justify">  <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves/> <w:TrackFormatting/> <w:PunctuationKerning/> <w:ValidateAgainstSchemas/> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF/> <w:LidThemeOther>EN-US</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>AR-SA</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables/> <w:SnapToGridInCell/> <w:WrapTextWithPunct/> <w:UseAsianBreakRules/> <w:DontGrowAutofit/> <w:SplitPgBreakAndParaMark/> <w:DontVertAlignCellWithSp/> <w:DontBreakConstrainedForcedTables/> <w:DontVertAlignInTxbx/> <w:Word11KerningPairs/> <w:CachedColBalance/> </w:Compatibility> <m:mathPr> <m:mathFont m:val="Cambria 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mso-para-margin-left:0in line-height:115% mso-pagination:widow-orphan font-size:11.0pt font-family:"Calibri","sans-serif" mso-ascii-font-family:Calibri mso-ascii-theme-font:minor-latin mso-fareast-font-family:"Times New Roman" mso-fareast-theme-font:minor-fareast mso-hansi-font-family:Calibri mso-hansi-theme-font:minor-latin mso-bidi-font-family:Arial mso-bidi-theme-font:minor-bidi} </style> </div><p style="margin-top: 5.65pt font-family: times new roman,times,serif text-align: justify" dir="rtl" class="BasicParagraph"><b><span lang="AR-YE">سابقه و هدف</span></b><span lang="AR-YE">: تاثیر عوامل محیطی در ایجاد سرطان مغز و اختلال در تقسیمات سلولی از اهمیت بسزایی برخوردار بوده و مورد نظر محققین قرار گرفته و ارزیابی و شناسایی می شود. هدف از انجام<span> </span>این مطالعه، بررسی تا ثیر فاکتورهای محیطی متفاوت مانند سن، جنس، وزن، عادات غذائی، میزان مصرف ویتامین ها، مشروبات الکلی و هم چنین سابقه خانوادگی در ایجاد سرطان مغز در بیمارانی که در بیمارستان شهدای تهران پذیرش شده بودند بود.</span></p><div style="text-align: justify"> </div><p style="font-family: times new roman,times,serif text-align: justify" dir="rtl" class="BasicParagraph"><b><span lang="AR-YE">مواد و روش ها</span></b><span lang="AR-YE">: برای این منظور پرسشنامه ای شامل سئوالاتی در مورد عوامل فوق در دسترس قرار گرفت. سپس مطالعات انجام شده توسط نرم افزار (</span><span lang="CA" dir="ltr">SPSS version 11</span><span dir="rtl"></span><span lang="AR-YE"><span dir="rtl"></span>) مورد تجزیه و تحلیل آماری قرار گرفت. این جامعه اماری شامل 100 بیمار مبتلا به سرطان مغز و 100 شخص سالم جهت کنترل بود.</span></p><div style="text-align: justify"> </div><p style="font-family: times new roman,times,serif text-align: justify" dir="rtl" class="BasicParagraph"><b><span lang="AR-YE">یافته ها</span></b><span lang="AR-YE">: بررسی های انجام شده نشان می دهد که رابطه مستقیمی بین مصرف بیش از حد گوشت قرمز و خطر ابتلا به سرطان مغز وجود دارد. افرادی که در رژیم غذائی شان از انواع ویتامین ها استفاده می کردند، تعداد کمی از مبتلایان را تشکیل می دادند. بین سن و جنسیت و خطر ابتلا به این بیماری رابطه معناداری گزارش نشده است. در حالی که میزان تحصیلات و در آمد نقش به سزائی در ابتلا افراد به این بیماری نشان داده است. همچنین مصرف بالای الکل و سیگار خطر ابتلا را افزایش داده است. رابطه مستقیمی نیز بین افرادی که سابقه خانوادگی مثبت داشتند و افزایش خطر ابتلا به سرطان مغز گزارش شده است. شغل افراد نیز یکی دیگر از فاکتورهای مهم محسوب می گردد چنان که درصد بالائی از بیماران مورد مطالعه در معرض اشعه </span><span dir="ltr">X</span><span dir="rtl"></span><span lang="AR-YE"><span dir="rtl"></span> بودند.</span></p><div style="text-align: justify"> </div><p style="font-family: times new roman,times,serif text-align: justify" dir="rtl" class="BasicParagraph"><b><span lang="AR-YE">نتیجه گیری</span></b><span lang="AR-YE"> : فاکتورهای محیطی نقش به سزائی در ایجاد سرطان مغز دارند.</span></p><div style="text-align: justify"> </div> <div style="text-align: justify">  <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves/> 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mso-hansi-font-family:Calibri mso-hansi-theme-font:minor-latin mso-bidi-font-family:Arial mso-bidi-theme-font:minor-bidi} </style>  </div><p style="direction: ltr unicode-bidi: embed font-family: times new roman,times,serif text-align: justify" class="BasicParagraph"><b><span lang="DA" style="font-size: 14pt line-height: 120%">Aim and Background</span></b><span lang="DA">: This study was aimed to determine the effect of different environmental factors in the incidence of brain cancer in patients admitted in Shohada Hospital Tehran. Dietary habits, vitamins, age, sex, education, occupation income, weight, cigarette smoking, alcohol consumption and family history were concerned as risk factors. </span></p><div style="text-align: justify"> </div><p style="direction: ltr unicode-bidi: embed font-family: times new roman,times,serif text-align: justify" class="BasicParagraph"><b><span lang="DA"></span><span lang="DA" style="font-size: 14pt line-height: 120%">Materials and Methods</span></b><span lang="DA">.The data were analyzed using the computer software SPSS for windows (version 11). The case-control study was conducted in 100 brain cancer patients and 100 healthy people as control.</span></p><div style="text-align: justify"> </div><p style="direction: ltr unicode-bidi: embed font-family: times new roman,times,serif text-align: justify" class="BasicParagraph"><b><span lang="DA" style="font-size: 14pt line-height: 120%">Results</span></b><span lang="DA">. An increased association was found with patients using non-vegetables such as red and white meat compared to control group which were mostly vegetarian. Low risk of brain cancer was also found among people using different vitamins daily. No association was observed with age and sex factors and risk of brain cancer. The analyzed factors like low income and low level of education also resulted in positive association with brain cancer. We also found statistically significant association between smoking habits, alcohol consumption and positive family history with brain cancer risk. Occupation was also found to be an important risk factor in this case-control study as patients working with radiography or X-ray instruments, showed a high frequency. </span></p><div style="text-align: justify"> </div><p style="direction: ltr unicode-bidi: embed font-family: times new roman,times,serif text-align: justify" class="BasicParagraph"><b><span lang="DA"></span><span lang="DA" style="font-size: 14pt line-height: 120%">Conclusion. </span></b><span lang="DA">This study shows that some of the environmental factors are important in increasing the risk of brain cancer.</span></p><div style="text-align: justify"> </div><div style="text-align: justify"> </div><p style="direction: ltr unicode-bidi: embed font-family: times new roman,times,serif text-align: justify" class="BasicParagraph"><span lang="DA"><br></span></p> سرطان مغز، فاکتورهای محیطی Brain Cancer, Environmental Factors 51 63 http://ncmbjpiau.ir/browse.php?a_code=A-10-2-20&slc_lang=fa&sid=1 Khadigeh Onsory خدیجه عنصری onsory@gmail.com 1003194753284600588 1003194753284600588 Yes Islamic Azad University, Parand Branch دانشگاه آزاد اسلامی واحد پرند samaneh Navabi ثمانه نوابی 1003194753284600589 1003194753284600589 No Department of Biology, Faculty of science, Islamic Azad University, Parand Branch دانشگاه آزاد اسلامی واحد پرند