fa بررسی اثرات پروبیوتیک لاکتوباسیلوس پلانتاروم بر ترمیم زخم پوستی در رت بیوشیمی Biochemistry مقاله پژوهشی Research Article <p style="TEXT-ALIGN: justify MARGIN: 0in 0in 0pt" dir="rtl" class="BasicParagraph" align="justify"><font size="3"><font face="times new roman,times,serif"><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE">سابقه و هدف</span></b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE">: پروبیوتیک ها میکروارگانیسم های موجود در لوله گوارش هستند که علاوه بر کمک به گوارش مولکول های پیچیده به سیستم </span></font></font><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE"><font size="3"><font face="times new roman,times,serif">ایمنی بدن نیز کمک کرده و باعث کاهش التهاب می شوند. اثرات سودمند این باکتری در ترمیم زخم های گوارشی به اثبات رسیده است اما تحقیقات کمی در زمینه اثرات ترمیمی این باکتری ها بر زخم های پوستی انجام شده است. هدف از این مطالعه، بررسی اثر لاکتوباسیلوس پلانتاروم جدا شده از محصولات لبنی- سنتی ایران بر ترمیم زخم پوستی می باشد.<p></p></font></font></span></p><p style="TEXT-ALIGN: justify MARGIN: 0in 0in 0pt" dir="rtl" class="BasicParagraph" align="justify"><font size="3"><font face="times new roman,times,serif"><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE">مواد و روش ها:</span></b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE"> پس از جداسازی 22 سویه لاکتوباسیل از محصولات لبنی- سنتی ایران و بررسی میزان تولید اگزو پلی ساکارید </span></font></font><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE"><font size="3"><font face="times new roman,times,serif">سویه ها با روش فنل سولفوریک در نهایت، لاکتوباسیلوس پلانتاروم که توانایی تولید اگزوپلی ساکارید بالایی داشت، انتخاب گردید. سپس </font></font></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE"><font size="3"><font face="times new roman,times,serif">موش های صحرایی نر از نژاد ویستار به گروه های پنج تایی تجربی، کنترل و کنترل منفی تقسیم شدند و زخمی مربع شکل به ابعاد</font></font></span><font size="3"><font face="times new roman,times,serif"><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" dir="ltr">cm</span><span dir="rtl"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE"><span dir="rtl"></span> 5/1 × 5/1 در پشت موش ها ایجاد گردید. پس از گذشت 24 ساعت از ایجاد زخم، گروه های کنترل و تجربی به ترتیب تحت درمان موضعی با اوسرین و اوسرین حاوی لاکتوباسیلوس پلانتاروم قرار گرفتند، اما گروه های کنترل منفی هیچ درمانی دریافت نکردند. مساحت زخم هر سه روز یک بار اندازه گیری شد. زخم پوستی موش ها پس از کشته شدن در روزهای یک، سه و چهارده برداشته شد و تحت مطالعات بافت شناسی و آماری قرار گرفت. <p></p></span></font></font></p><p style="TEXT-ALIGN: justify MARGIN: 0in 0in 0pt" dir="rtl" class="BasicParagraph" align="justify"><font size="3"><font face="times new roman,times,serif"><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE">یافته ها</span></b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE">: لاکتوباسیلوس پلانتاروم ابعاد زخم را نسبت به دو گروه کنترل و کنترل منفی به طور معنی داری کاهش و ترمیم زخم را افزایش داد. بررسی </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">مطالعات</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">بافت</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">شناسی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">در</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">روز</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">سوم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">نشان</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">دهنده</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">افزایش</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">معنی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">دار</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">میزان</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">نوتروفیل</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ها</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">در</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">واحد</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">سطح</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" dir="ltr">(</span><span dir="rtl"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-bidi-language: FA" lang="FA"><span dir="rtl"></span>0.001</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span><P) </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">و</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">افزایش</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ماکروفاژها</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">و</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span>  </span></font></font><font size="3"><font face="times new roman,times,serif"><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">فیبروبلاست</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ها</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">بود</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span dir="rtl"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi" lang="AR-YE"><span dir="rtl"></span>(</span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-bidi-language: FA" lang="FA">0.001</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span><P). </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">همچنین</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">در</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">روز</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">چهاردهم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">در</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">میزان</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">نوتروفیل</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ها،</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ماکروفاژها</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">و</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">فیبروبلاست</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ها</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">کاهش</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">معنی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">دار</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span> (</span><span dir="rtl"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-bidi-language: FA" lang="FA"><span dir="rtl"></span>0.001</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span><P) </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">مشاهده</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">شد</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span>.<p></p></span></font></font></p><p style="TEXT-ALIGN: justify MARGIN: 0in 0in 0pt" dir="rtl" class="BasicParagraph" align="justify"><font size="3"><font face="times new roman,times,serif"><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">نتیجه</span></b><span dir="ltr"></span><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span></b><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">گیری</span></b><span dir="ltr"></span><b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span>:</span></b><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">یافته</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">های</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">فوق</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">نشان</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">دادند</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">که</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">لاکتوباسیلوس</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">پلانتاروم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">توانسته</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">به</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">طور</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">معنی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">داری</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">موجب</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">کاهش</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">التهاب</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">و</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">تسریع</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">روند</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">بهبود</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">زخم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">در</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">موش</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">صحرایی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">شود</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span>. </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">مطالعات</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">بیشتری</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">جهت</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">شناسایی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">دقیق</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">تر</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">مکانیسم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">عمل</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">لاکتوباسیلوس</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">پلانتاروم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">در</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">طی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">ترمیم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">زخم</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">پوستی</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">نیاز</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="AR-YE"><span dir="ltr"></span> </span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" lang="AR-YE">است</span><span dir="ltr"></span><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span dir="ltr"></span>.<p></p></span></font></font></p><p style="TEXT-ALIGN: justify MARGIN: 0in 0in 0pt" dir="rtl" class="BasicParagraph" align="justify"><font size="3"><font face="times new roman,times,serif"><span style="mso-ascii-font-family: 'Times New Roman' mso-ascii-theme-font: major-bidi mso-hansi-font-family: 'Times New Roman' mso-hansi-theme-font: major-bidi mso-bidi-font-family: 'Times New Roman' mso-bidi-theme-font: major-bidi mso-ansi-language: CS" dir="ltr" lang="CS"><span style="mso-spacerun: yes"></span></span></font></font><font face="times new roman,times,serif"></font></p> <p align="justify"><font face="times new roman,times,serif"><font size="3"><strong> Aim and Background. </strong>Probiotics are microorganisms in the gastrointestinal tract that besides helping the digestion of complex molecules, also helped the immune system and will reduce inflammation. The beneficial effects of these bacteria on ulcer healing has been proved but little research has been don done in the field of healing effects of these bacteria on cotaneous wound healing. Therefore, the purpose of this experiment is study the effect of lactobacillus plantarum isolated from Iranian traditional dairy products on cutaneous wound healing. </font></font></p><p align="justify"><font size="3" face="times new roman,times,serif"><strong>Materials and Methods. </strong>After isolated 22 strains of lactobacillus from Iranian traditional-dairy products and measuring exopolysaccharide production in stains by phenol-sulfuric acid method eventually, </font><font size="3" face="times new roman,times,serif">Lactobacillus plantarum selected because it has a high exopolysaccharide (EPS) production. Wistar male rats divided into 3 groups experimental, control and negative control (n=5) and a full-thickness wound </font><font size="3" face="times new roman,times,serif">  (1.5 × 1.5 cm) was made on the back of each rat (45 rats in 3 groups). After 24 hours of injury, Two groups, control and experimental, were treated by eucerin and eucerin contained lactobacillus plantarum, respectively, but the negative-control group did not receive anything. On days 1, 3 and 14 rats were killed and wound samples were collected for histological and statistical studies. </font></p><p align="justify"><font size="3" face="times new roman,times,serif"><strong>Results </strong>. Lactobacillus plantarum significantly decreased wound area compared to control and negative </font><font size="3" face="times new roman,times,serif">control groups and increased wound healing. Histological study on day 3 showed significant increase in </font><font size="3" face="times new roman,times,serif"> number of neutrophils and significant increases in macrophages and fibroblasts (p<0.001). Also significant reduction in neutrophils, macrophages and fibroblasts numbers observed on day 14 (p<0.001). </font></p><p align="justify"><font size="3" face="times new roman,times,serif"><strong>Conclusions </strong>: The current study presented a significant decrease in inflammation and an acceleration of wound healing in Lactobacillus plantarum treated rats as compared to the control and negative control groups. Further studies are required to develop a detailed mechanism of Lactobacillus plantarum during cutaneous wound healing. </font></p><p align="justify"><font size="3" face="times new roman,times,serif"></font></p><p align="justify"><font size="3" face="times new roman,times,serif">  </font></p> زخم پوستی، ترمیم، پروبیوتیک، لاکتوباسیلوس پلانتاروم، اگزوپلی ساکارید Cutaneous wound, Probiotic, Healing, Lactobacillus palantarum, Exopolysaccharid 21 27 http://ncmbjpiau.ir/browse.php?a_code=A-10-2-3&slc_lang=fa&sid=1 Mitra Heydari nasrabadi میترا حیدری نصرآبادی 1003194753284600569 1003194753284600569 Yes Islamic Azad University, parand branch, Sceince faculty, Biology Department دانشگاه آزاد اسلامی پرند، دانشکده ی علوم، گروه زسیت شناسی Maryam Tajabadi ebrahimi مریم تاج آبادی ابراهیمی 1003194753284600570 1003194753284600570 No Islamic Azad University, Tehran Central branch, Biology Department دانشگاه آزاد اسلامی، واحد تهران مرکز، گروه زیست شناسی Shokofeh Dehghan Bonadaki شکوفه دهقان بنادکی 1003194753284600571 1003194753284600571 No Islamic Azad University, parand branch, Sceince faculty, Biology Department دانشگاه آزاد اسلامی واحد پرند، دانشکده ی علوم زیستی، گروه زیست شناسی Mansoreh Torabi kajousangi منصوره ترابی کجوسنگی 1003194753284600572 1003194753284600572 No Islamic Azad University, Science faculty, Biology Department دانشگاه آزاد اسلامی واحد پرند، دانشکده ی علوم، گروه زیست شناسی Farimah Zahedi فریما زاهدی 1003194753284600573 1003194753284600573 No Islamic Azad University, parand branch, Sceince faculty, Biology Department دانشگاه آزاد اسلامی واحد پرند، دانشکده ی علوم، گروه زیست شناسی