Volume 9, Issue 34 (4-2019)
NCMBJ 2019, 9(34): 47-56 |
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Firoozeh E, Khodarahmi P, Naseh V, Shahedi V, Golgoo F, mohammad yari S. Synergistic Effect Of Treadmill Exercise And Green Tea Extract On Cutaneous wound Healing In Diabetic Mice. NCMBJ 2019; 9 (34) :47-56
URL: http://ncmbjpiau.ir/article-1-1187-en.html
URL: http://ncmbjpiau.ir/article-1-1187-en.html
Elham Firoozeh 
, Parvin Khodarahmi , Vahid Naseh , Valiollah Shahedi , Farzaneh Golgoo , sajjad Mohammad yari
, Parvin Khodarahmi , Vahid Naseh , Valiollah Shahedi , Farzaneh Golgoo , sajjad Mohammad yari
Department of Biology, Faculty of Life Sciences, Islamic Azad University, Parand Parand, Parand, Iran , Vahid55vet@yahoo.com
Abstract: (4228 Views)
Aim and Background:
In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.
Material and methods:
The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic exercise - diabetic and immobile with green tea extract , diabetic with synergism of exercise and green tea extract. After inducing of diabetes using sterptozotocin mice were killed and in days 3-7-14-21 macroscopic and histopathologic analysis were performed.
Results:
The results indicated that in synergistic group of green tea extract and treadmill exercise , wound area decreased and fibroblast increased after 7 days significantly compared with other groups (p<0.001).PMN cells decreased after 3 days significantly compared with other groups (p<0.001).
Conclusion:
The results suggest that green tea extract and treadmill exercise have synergistic effect on wound healing in diabetic mice.
In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.
Material and methods:
The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic exercise - diabetic and immobile with green tea extract , diabetic with synergism of exercise and green tea extract. After inducing of diabetes using sterptozotocin mice were killed and in days 3-7-14-21 macroscopic and histopathologic analysis were performed.
Results:
The results indicated that in synergistic group of green tea extract and treadmill exercise , wound area decreased and fibroblast increased after 7 days significantly compared with other groups (p<0.001).PMN cells decreased after 3 days significantly compared with other groups (p<0.001).
Conclusion:
The results suggest that green tea extract and treadmill exercise have synergistic effect on wound healing in diabetic mice.
Type of Study: Research Article |
Subject:
Cellular and molecular
Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16
Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16
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