Volume 9, Issue 34 (4-2019)
NCMBJ 2019, 9(34): 47-56 |
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Firoozeh E, Khodarahmi P, Naseh V, Shahedi V, Golgoo F, mohammad yari S. Synergistic Effect Of Treadmill Exercise And Green Tea Extract On Cutaneous wound Healing In Diabetic Mice. , NCMBJ. 2019; 9 (34) :47-56
URL: http://ncmbjpiau.ir/article-1-1187-en.html
URL: http://ncmbjpiau.ir/article-1-1187-en.html
Elham Firoozeh 
, Parvin Khodarahmi , Vahid Naseh * , Valiollah Shahedi , Farzaneh Golgoo , sajjad Mohammad yari
, Parvin Khodarahmi , Vahid Naseh * , Valiollah Shahedi , Farzaneh Golgoo , sajjad Mohammad yari
Department of Biology, Faculty of Life Sciences, Islamic Azad University, Parand Parand, Parand, Iran , Vahid55vet@yahoo.com
Abstract: (5886 Views)
Aim and Background:
In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.
Material and methods:
The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic exercise - diabetic and immobile with green tea extract , diabetic with synergism of exercise and green tea extract. After inducing of diabetes using sterptozotocin mice were killed and in days 3-7-14-21 macroscopic and histopathologic analysis were performed.
Results:
The results indicated that in synergistic group of green tea extract and treadmill exercise , wound area decreased and fibroblast increased after 7 days significantly compared with other groups (p<0.001).PMN cells decreased after 3 days significantly compared with other groups (p<0.001).
Conclusion:
The results suggest that green tea extract and treadmill exercise have synergistic effect on wound healing in diabetic mice.
In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.
Material and methods:
The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic exercise - diabetic and immobile with green tea extract , diabetic with synergism of exercise and green tea extract. After inducing of diabetes using sterptozotocin mice were killed and in days 3-7-14-21 macroscopic and histopathologic analysis were performed.
Results:
The results indicated that in synergistic group of green tea extract and treadmill exercise , wound area decreased and fibroblast increased after 7 days significantly compared with other groups (p<0.001).PMN cells decreased after 3 days significantly compared with other groups (p<0.001).
Conclusion:
The results suggest that green tea extract and treadmill exercise have synergistic effect on wound healing in diabetic mice.
Type of Study: Research Article |
Subject:
Cellular and molecular
Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16
Received: 2019/03/16 | Accepted: 2019/03/16 | Published: 2019/03/16
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