Volume 10, Issue 37 (12-2019)
NCMBJ 2019, 10(37): 53-64 |
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Sadrodin Karami N, Zia Jahromi N, Hejazi S H, Ajami A. The relationship between HbA1c and microalbuminuria in type II diabetic patients in Isfahan province. NCMBJ 2019; 10 (37) :53-64
URL: http://ncmbjpiau.ir/article-1-1246-en.html
URL: http://ncmbjpiau.ir/article-1-1246-en.html
The relationship between HbA1c and microalbuminuria in type II diabetic patients in Isfahan province
Department of Biology, Science Faculty, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
Abstract: (3662 Views)
Aim and Background: The increase in kidney disease is partly due to an increase in the prevalence of diabetes. Type 2 diabetes often occurs in adults.. The aim of this study was to investigate the relationship between HbA1c and microalbuminuria in type II diabetic patients in Isfahan province by biochemical methods.
Materials and Methods: In this study, 50 patients with type II diabetes and 50 healthy subjects were blood samples. Also, microalbumin was collected from both groups of 24-hour urine samples. Then, HbA1c was measured by HPLC method and the microalbumin content of the specimen was measured by Immunoturbidimetric method. Data analysis was done using SPSS software. Comparison of quantitative data was performed using T-test, qualitative data with A, qualitative data with Chi-square test and U Mann Whiteny test.
Results: The results indicate that with increasing levels of HbA1c , the rate of microalbumin release also increases in type II diabetic patients. Biochemical indices such as FBS, BUN, Cr, U.Acid, potassium, serum albumin were significantly higher in the control group than in the control group.
Conclusion: According to the results obtained from this study, it can be concluded that type 2 diabetes mellitus causes an imbalance in the excretion of microalbumin from the kidney. Also, the study of HbA1c is a useful parameter in the evaluation of type 2 diabetes.
Keywords: Type II diabetes, Microalbuminuria, HbA1c.Type II diabetes, Microalbuminuria, HbA1c, IAU-science
Type of Study: Research Article |
Subject:
Cellular and molecular
Received: 2019/12/5 | Accepted: 2019/12/5 | Published: 2019/12/5
Received: 2019/12/5 | Accepted: 2019/12/5 | Published: 2019/12/5
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