Volume 5, Issue 18 (4-2015)                   NCMBJ 2015, 5(18): 83-88 | Back to browse issues page

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Salehi M, Tabibzadeh M, Fallahian M R. Prevalence of qnr gene in clinical Acinetobacter isolates. NCMBJ. 2015; 5 (18) :83-88
URL: http://ncmbjpiau.ir/article-1-632-en.html
Islamic Azad University, North Tehran Branch, Iran , mahnaz33082@gmail.com
Abstract:   (9760 Views)

Aims and Background: This study investigated the prevalence of qnr genes and resistance to fluoroquinolone antibiotics among clinical isolates of Acinetobacter in Tehran.
Materials and Methods: Prevalence of qnr genes among Acinetobacter isolates were determined by PCR technique. Also by the use of antibiogram method, susceptibility of isolates against the fluoroquinolone family of antibiotics, piperacillin-tazobactam, and colistin were examined.
Results: Evaluation of PCR in the 50 qnr-positive Acinetobacter isolates showed that 74% of them had qnrA and 22% had qnrB. Almost all of isolates were resistant to the fluoroquinolones.

Conclusion: This study showed a high prevalence of qnr genes and a higher prevalence of genotype qnrA than qnrB.

Full-Text [PDF 448 kb]   (1171 Downloads)    
Type of Study: Research Article | Subject: Cellular and molecular
Received: 2015/05/31 | Accepted: 2015/05/31 | Published: 2015/05/31

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