Volume 12, Issue 46 (3-2022)
NCMBJ 2022, 12(46): 45-54 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Hemati M, Keshtmand Z, Borhani K. The effect of silver nanoparticles on the viability of normal skin cells (MHFB-1). NCMBJ 2022; 12 (46) :45-54
URL: http://ncmbjpiau.ir/article-1-1455-en.html
URL: http://ncmbjpiau.ir/article-1-1455-en.html
Department of Environment and Food industry Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Abstract: (2009 Views)
Aim and Background: Silver nanoparticles (AgNPs) have been considered by researchers as a very strong inhibitor due to their biological properties and have many applications in prevention and treatment. However, there is little information about the effect of nanoparticles on healthy cells.The aim of this study was to investigate the effect of silver nanoparticles on the viability percentage of normal skin cell line MHFB-1.
Material and methods:In this study, during 24, 48 and 72 hours, different concentrations of silver nanoparticles (1.56, 3.125, 6.25, 12.5, 25, 50 and 100 μg / ml on MHFB-1 cell line was evaluated by MTT method.Data obtained from the test were statistically analysed using SPSS software, one-way ANOVA, Tukey test and significance level of P <0.05.
Results: Treatment of normal MHFB-1 cells with different concentrations of silver nanoparticles after 24, 48 and 72 hours by MTT method showed a significant reduction in the viability of cells at concentrations of 25, 50 and 100 μg /ml.
Conclusion: Conclusion: The results of this study showed a dose-dependent inhibitory effect of silver nanoparticles on normal skin cell line (MHFB-1).
Material and methods:In this study, during 24, 48 and 72 hours, different concentrations of silver nanoparticles (1.56, 3.125, 6.25, 12.5, 25, 50 and 100 μg / ml on MHFB-1 cell line was evaluated by MTT method.Data obtained from the test were statistically analysed using SPSS software, one-way ANOVA, Tukey test and significance level of P <0.05.
Results: Treatment of normal MHFB-1 cells with different concentrations of silver nanoparticles after 24, 48 and 72 hours by MTT method showed a significant reduction in the viability of cells at concentrations of 25, 50 and 100 μg /ml.
Conclusion: Conclusion: The results of this study showed a dose-dependent inhibitory effect of silver nanoparticles on normal skin cell line (MHFB-1).
Type of Study: Research Article |
Subject:
Cellular and molecular
Received: 2021/04/1 | Accepted: 2021/09/2 | Published: 2022/04/11
Received: 2021/04/1 | Accepted: 2021/09/2 | Published: 2022/04/11
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
