Volume 5, Issue 17 (3-2015)
NCMBJ 2015, 5(17): 57-67 |
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Alishiri A, Rakhshandehroo F, Zamanizadeh H. Using viruses as carriers for drug delivery. NCMBJ 2015; 5 (17) :57-67
URL: http://ncmbjpiau.ir/article-1-322-en.html
URL: http://ncmbjpiau.ir/article-1-322-en.html
Science and Research Branch, Islamic Azad University , hzamani@gmail.com
Abstract: (8745 Views)
Introduction: new nano-carrier platforms based on natural biological building blocks offer great promises in revolutionizing medicine.
Materials and methods: The usage of specific protein cage structures such as virus-like particles (VLPs) for drug packaging and targeted delivery has attracted much attention.
Results: versatile chemical and genetic modifications on the outer surfaces and inner cavities of VLPs facilitate the preparation of new materials requirements for drug delivery.
Discussion: A full evaluation on the toxicity, biodistribution and immunology of these materials are envisaged to boost their application potentials. Results: VLPs can easily offer the requirements that are needed for a drug delivery, such as biocompatibility, solubility in water, and high uptake efficiency.
Materials and methods: The usage of specific protein cage structures such as virus-like particles (VLPs) for drug packaging and targeted delivery has attracted much attention.
Results: versatile chemical and genetic modifications on the outer surfaces and inner cavities of VLPs facilitate the preparation of new materials requirements for drug delivery.
Discussion: A full evaluation on the toxicity, biodistribution and immunology of these materials are envisaged to boost their application potentials. Results: VLPs can easily offer the requirements that are needed for a drug delivery, such as biocompatibility, solubility in water, and high uptake efficiency.
Type of Study: Review Article |
Subject:
Immonology
Received: 2013/05/8 | Accepted: 2015/01/26 | Published: 2015/02/24
Received: 2013/05/8 | Accepted: 2015/01/26 | Published: 2015/02/24
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