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Aim and Background: Programmed cell death (PCD) is involved in plant resistance responses to pathogens and environmental biotic and abiotic stresses and its function has been conserved in eukaryotes, plant and animal phylum's. Material and Methods: In many human diseases such as the respiratory disorders and nervous related diseases such as the Alzheimer and Parkinson, it is observed that the PCD process is non functional and unregulated processed and does not work. Results: Different genes related to this biological mechanism in plants were identified by the researchers and the conserved genetical and biochemical pathways involved in activating the PCD almost fully determined. Discussion: Although, some of the morphological and biochemical changes that are generally occur in PCD in animals are also observe in plants, but there is a few knowledge available about how these process lead to cell death in plants Conclusion: Regardless of the fact that the programmed cell death appear to be a conserved process in animals and plant cells but from the genetical and biochemical point of view it take place completely different in plants.

Keywords: PCD, Apoptosis, HR, DNA, molecular pathways

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