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Aim and Background: One of the most common acquired infections is urinary tract infections (UTI). This problem is associated with the wild antibiotics treatment for UTI. In this study, the effect of zangaber extracts were compared with antibiotics for treatment of UTI . Materials and Methods: 100 samples were isolated from patients with UTI. Bacteria were identified with biochemical tests. Then was used antibiogram with different antibiotics and resistant bacteria were isolated. Antibacterial effect of different concentrations from zangaber extracts were tested on resistant bacteria. Results:From 100 isolates, 46 samples were E. coli, 10 were Proteus mirabilis, 9 were Pseudomonas aeruginosa, 5 were Staphylococcus aureus, and 30 samples were other bacteria. The lowest MIC for E. coli was found Nitrofurantoin and Nalidixica cid, Ceftriaxone and Cephazolin were for Proteus mirabilis, Pseudomonas aeruginos and Staphylococcus aureus. The highest MIC for zangaber was found by methanolic extract of zangaber. Conclusion: Results have shown most of bacteria have become resistant to antibiotics. As also, by increasing of antibiotic application for UTI treatment was produced resistance bacteria, therefore plant drugs with antibacterial effects such as zangaber is required. This plant can be inhibited of uropathogenic bacteria.

Keywords: Antibiotic Resistance, Zangaber extract, Urinary Tract Infection

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