Volume 1, Issue 2 (4-2011)                   NCMBJ 2011, 1(2): 61-65 | Back to browse issues page

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Naseri M, Heydari nasrabadi M, Khodarahmi P, Ahmadi F, Mojibi P, Abotalebei H. Study of the Effect of Fumaria parviflora Alcoholic Extract on Spermatogenesis in Male Rats. NCMBJ. 2011; 1 (2) :61-65
URL: http://ncmbjpiau.ir/article-1-24-en.html
Islamic Azad University Parand branch, Science Faculty, Biology Department
Abstract:   (28739 Views)
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Aim and Background. Spermatogenesis is a process In which spermatozoids Is produced Whose defect in each stepany defect in each step can Can result result in infertility. F. parviflora contains isoquinoline and protopine alkaloids and h as antioxidant activity. F. parviflora has been used in folk medicine for its pharmaceutical properties. One of the most important effects of this plant is increasing sexuality. The aim of this study is to investigate the effect of the F. parviflora alcoholic extract in spermatogenesis process.

 

Materials and Methods. Wistar male rats (230 ± 5) are divided into 2 groups: control and experimental. The control group received distilled water whereas the experimental group received 250 mg/kg w.b. F. parviflora alcoholic extract through oral gavage for 5 days. After 15 days rats were anesthesized and sacrificed and the Testis were removed. The volume and weight of the testis were measured and the tissues were fixed. The preparation of tissue sectioning was accomplished by H&E staining. Germinal cell lines cells were counted with light microscope. Statistical analysis was performed with One Way Anova using SPSS for Windows.P ≤0.05 was considered statistically significant.

 

Results. The analysis of the results indicated there were no significant difference in weight and volume of testicles but significant increase in the number of spermatogonia ,spermatocytes ,spermatozoid and Leydig cells were observed in experimental group compared to the control group (P<0.001).

Conclusions.The results indicated positive effect of F. parviflora alcoholic extract on male reproductive system Since the number of number of sexual cells increased significantly.

 
 
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Type of Study: Research Article | Subject: Physiology
Received: 2011/05/5 | Accepted: 2014/04/23 | Published: 2014/04/23

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